Glutamine is vital for natural pumps

You’ve been hearing it for years from bodybuilders, doctors and chemists: When it comes to getting a pump, enhancing blood flow, increasing muscular contraction quality and more, arginine in its various forms is king. But a new German study shows that arginine isn’t the only kid in town. Enter glutamine.

Researchers examined the metabolism of glutamine, arginine and citrulline. They found that glutamine contributes 64 percent of the arginine production that results from a single dose of citrulline. The researchers concluded that glutamine is important for natural arginine production.


Arginine may be important for the pump, enhanced blood flow, increased muscular contraction quality and more, but glutamine plays a central role in arginine production. No glutamine, no arginine. No arginine, no pump. It’s pretty clear that you need glutamine, so if you want to get pumped and build a bigger physique, get on glutamine! It’s best to take glutamine in four equal doses per day of 5 grams each on an empty stomach – once upon rising, once before your workout, once after your workout and once again prior to bed.


Ligthart-Melis GC, van de Poll MC, Boelens PG, Dejong CH, Deutz NE, van Leeuwen PA. Glutamine is an important precursor for de novo synthesis of arginine in humans. Am J Clin Nutr. 2008 May;87(5):1282-9.

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